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pentobarbital will lessen the extent or result of eplerenone by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Insignificant/Importance Mysterious.pentobarbital decreases effects of sufentanil SL by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Observe Carefully. Coadministration of CYP3A4 inducers may possibly low